2. Relevance to Public Health 2.1 Background and Environmental Exposures to 1,4-dioxane in the United States

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1,4-Dioxane is a stable, clear liquid at ambient temperatures and is miscible with water. It is used primarily as a solvent for chemical processing. It has also been used as a laboratory reagent; in plastic, rubber, insecticides, and herbicides; as a chemical intermediate; as part of a polymerization catalyst; and as an extraction medium of animal and vegetable oils. 1,4-Dioxane may also be found as a contaminant in ethoxylated surfactants, which are used in consumer cosmetics, detergents, and shampoos. Currently, manufacturers remove 1,4-dioxane from ethoxylated surfactants to low levels by vacuum stripping.

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تاریخ انتشار 2012